March 18th, 2012
Sadness, grief, anxiety…

… all gone!

In the age of Big Pharma, we have, of course come to medicalize [anxious] thoughts — not to mention just about every other whim and pang. When I once confided with a physician friend that one of my children seemed to overheat with anxiety around tests, he smiled kindly and literally assured, “No need to worry about that, we have a cure for anxiety today.” On current reckoning, anxiety is a symptom, a problem, but Kierkegaard insists, “Only a prosaic stupidity maintains that this (anxiety) is a disorganization.” And again, if a “speaker maintains that the great thing about him is that he has never been in anxiety, I will gladly provide him with my explanation: that is because he is very spiritless. ”

March 18th, 2012
The Grief Cure

“It is not a disease and it has no place in a book dedicated to listing mental disorders,” write two observers in Slate, as they anticipate (dread, really… dread is probably a billable disorder too… or will soon be…) the phenomenon of our grief at the loss of people we love entering the Diagnostic and Statistical pantheon. “The new diagnosis, spearheaded by two professors of psychiatry, Katherine Shear and Holly Prigerson, at Columbia and Harvard University,” will go after melancholic malingerers, sickos who stay sad beyond happiness’s due date.

So what are the downsides of treating grief as a disease? For one thing, more people will be prescribed antidepressants that can have adverse physical and psychological side effects, including increased risk of suicide and addiction and withdrawal problems. (To date, the research has consistently shown that grief counseling and medications do not alleviate grief; they seem most helpful in the cases of people who had pre-existing mental health issues.) It also means that more people will feel shame and embarrassment about not grieving “properly” or getting over their loss fast enough. And the very language of “symptoms” and “duration” seems only to further diminish the significant event that precipitated these feelings in the first place — the death of a beloved person who can’t be replaced.

On the other hand – America’s already crawling with millions of people who shouldn’t be on antidepressants – what’s a few more? C’mon in! Water’s fine!

And there’s so much money in it. Think of it! Convincing non-mourning people they’re depressed is tricky – you need wall-to-wall advertisements. Convincing mourning people? Piece of cake.

**********************************

Once pill distribution begins, mentally disordered poems like this one will be a thing of the past:

The Eden of the Author of Sleep
By Brian Teare

for Jean

And sleep to grief as air is to the rain,
upon waking, no explanation, just blue

spoons of the eucalyptus measuring
and pouring torrents. A kind of winter.

As if what is real had been buried
and all sure surfaces blurred. Is it me

or the world, risen from beneath?
Mind refining ruin, or an outside

unseen hand, working—as if with
a small brush, for clarity—the details?

To open my eyes is the shape of a city
rising slowly through sand. Cloudy

quartz, my throat, cut unadorned
from the quarry, stone of city cemetery

and roads, to breathe is a mausoleum
breached. To think of Eden is speech

to fill a grave, tree in which knowledge
augurs only its limits, the word snake

a thought crawling in the shadow
of its body. Was it, Adam, like this

always, intellect in the mind’s small sty
miming confinement for meaning, sleep

to grief as air is to the rain, upon waking,
the world’s own weapons turned against it—

********************************************

I mean, just look at this guy, luxuriating in it (how long has it been since his dedicatee died, I wonder?), wallowing in his misery instead of getting over it!

The Eden of the Author of Sleep

By Brian Teare

for Jean

And sleep to grief as air is to the rain,

[Lost in vaporous air. Disturbing symptom right off the bat. Sleep disturbance.]

upon waking, no explanation, just blue

spoons of the eucalyptus measuring
and pouring torrents. [Describes himself as permanently under a rainstorm. Classic sign of depression. Nice assonance on the u‘s of blue, spoons, eucalyptus, by the way.] A kind of winter.

As if what is real had been buried
and all sure surfaces blurred. [Diminished sense of reality. Pre-psychotic.] Is it me

or the world, risen from beneath? [It’s you. Consult your doctor.]
Mind refining ruin, or an outside

unseen hand, working — is if with
a small brush, for clarity — the details? [Mentally going over and over the details of the lost loved person, life before, whatever. ]

To open my eyes is the shape of a city
rising slowly through sand. [Slowed thoughts – Depression 101.] Cloudy

quartz, my throat, cut unadorned
from the quarry, stone of city cemetery [Strikingly morbid poem.]

and roads, to breathe is a mausoleum
breached. [Reports feeling that every breath he takes is an approach to the loved one’s grave. Abnormal.] To think of Eden is speech

to fill a grave, tree in which knowledge
augurs only its limits, the word snake

a thought crawling in the shadow
of its body. [Hopelessness. Words seem meaningless, understanding impossible.] Was it, Adam, like this

always, intellect in the mind’s small sty
miming confinement for meaning, [Seems to feel he can only function by becoming a mental midget.] sleep

to grief as air is to the rain, [Note the recurrence of this phrase. Circular thinking.] upon waking,
the world’s own weapons turned against it— [Clear cry for help here.]

March 15th, 2012
A Bear of Very Pilled-Up Brain.

UD thanks Dirk.

March 15th, 2012
Amazing Results

In academia, the competition for grant money and prominent journal publication breeds exaggeration as to the importance of research programs, their past successes, and their future chances. The worst of these cross over the line into fraud, some of which makes the headlines, but even the honest stuff (the huge majority) is best-foot-forward all the time. You learn, after a short time doing research yourself, to mentally adjust for the titles of papers, presentations, and (most especially) press releases.

Derek Lowe reminds us of a basic and abiding truth behind many of the posts on this blog, and other blogs, like Health Care Renewal and Retraction Watch: The system’s pretty well rigged against strict research integrity, a fact that endangers universities in particular and everyone’s health in general.

***********************

UPDATE: A Case in Point.

Brown’s cozy friendship with pharmaceutical companies should concern every one of us. The University’s failure to launch a public investigation into Keller’s research threatens the integrity of other research coming from Brown. Not only does it discredit Brown’s integrity as a research university, but it also threatens patient safety since doctors are misinformed about the negative side-effects of drugs they are prescribing. The University should be devoted to researching medicine for the sake of benefiting humanity, not corporate profits.

An eloquent opinion piece by a Brown University undergrad revisits the ongoing scandal of Martin Keller. Background here.

UD thanks Roy.

March 5th, 2012
Aussie Pseuds

UD has been following the effort of legitimate scientists in Australia to keep pseudo-science out of university classrooms there.

I mean, it’s already in. There’s lots of reflexology and aromatherapy and shit in Australian university curricula. The Friends of Science in Medicine are trying get some of that out, and to prevent new stuff from entering.

The real leader in these legitimizing efforts is England, which has not only been making it more difficult for doctors there to throw antidepressants around like candy (for many people, they seem to be expensive, side-effect-ridden, placebos), but has also made it “no longer … possible to receive degrees in alternative medicine from publicly funded universities.”

UD‘s US of A has also been good at keeping out the pseuds (see Florida State’s successful battle to break the back of the chiropractors), but backwaters like Australia will take longer to grasp the concept of empiricism. We must be patient with them.

In time, Australia will do what we’ve done here – establish a system of diploma mills that hand out Decompression Therapy degrees.

Some of the arguments the cornered pseuds make are quite something. One popular line is that you want pseuds in college rather than out, because they may as well get some training – it’s less dangerous to the general population that way. As the head of an Aussie pseud group pompously puts it: “In order to safeguard the public, practitioners of these modalities need to be part of the same rigorous training and education as other health professionals.” Yeah and there’s mucho, mucho modalities out there, aren’t there… So… you want to safeguard the population by putting all the modalities in the university. Millions of people organize their lives around what astrologers tell them, and yet we have no way of being sure those astrologers are properly trained, so we need to offer PhDs in astrology.

————————–

UD thanks Dirk.

March 4th, 2012
‘ONE OUT OF EVERY TEN WALL STREET EMPLOYEES IS A PSYCHOPATH, SAY RESEARCHERS’

Although UD loves this headline, it made her laugh, it’s fun fun fun, she can already see its inclusion in Occupy Wall Street’s Statement of Principles — she feels bound to remind herself, and you, her reader, of what psychological studies are worth these days.

In recent years, psychologists have reported a raft of findings on race biases, brain imaging and even extrasensory perception that have not stood up to scrutiny.

… In a survey of more than 2,000 American psychologists scheduled to be published this year, Leslie John of Harvard Business School and two colleagues found that 70 percent had acknowledged, anonymously, to cutting some corners in reporting data. About a third said they had reported an unexpected finding as predicted from the start, and about 1 percent admitted to falsifying data.

I’m just telling you this so that when in fact only one out of every thirty Wall Street employees turns out to be a psychopath you won’t be disappointed.

February 24th, 2012
Sigh. When you see these bullshit webpages…

… alarms really should go off. You shouldn’t be surprised that people like Bharat B. Aggarwal are under investigation for

fabrication and falsification in a host of published studies [65 and counting, to be precise] about the cancer-fighting properties of plants.

I mean, look at the page, please. This person tells us he has seven professorships:

Member, University of Texas Graduate School of Biomedical Sciences, Houston

Adjunct Professor at Albert B. Alkek Institute of Biosciences and Technology (IBT), Texas A&M University, Houston

Ransom Horne, Jr. Distinguished Professor of Cancer Research

Professor of Cancer Medicine

Professor of Immunology

Professor of Biochemistry and Professor of Experimental Therapeutics

Chief, Cytokine Research Section, in the Department of Experimental Therapeutics at the University of Texas M. D. Anderson Cancer Center, Houston, Texas

He’s published over six hundred papers… Of course, this number doesn’t raise eyebrows because other med professors say they’ve published a thousand… two thousand… a zillion squared…. When you’re one of thirty authors listed at the top of a page, when you’re a lab chief who probably did squat on most of the studies, the sky’s the limit. Go for it.

You’re seven professors at once, and you’ve published six hundred papers, and you’ve been invited to give 324 lectures in fifty countries… But you still have time to

[manipulate your] images – adding or subtracting features, cropping, stretching, rotating, flipping horizontally or vertically – to leave the impression the same ones represented different experimental conditions.

February 24th, 2012
Return with us now to those thrilling days of yesteryear…

… when asbestos companies could sponsor industry-friendly research at some of our best universities!

A letter signed by dozens of prominent scientists, including some McGill faculty members, was sent to McGill’s top administrators the same day a documentary aired on CBC Television on the [asbestos industry]. Both the letter and the documentary suggested McGill researchers had been paid by the … industry to doctor research to make chrysotile asbestos seem less harmful to human health than it is, or than other forms of the fibrous mineral.

Back in ’02, a Brown University professor made the same claim to McGill, but I guess since it just came from one guy they dismissed it. Now a crowd seems to be forming.

February 20th, 2012
“Where does it end? Do we keep everyone sedated constantly, just in case?”

The Australian commenter posing this question can look over here, at the States, to see what a national sedation policy might look like.

Not that every one of us has been zoned by Zeneca… mummified by Merck… Lalalanded by Lilly… but, you know, tens of millions of Americans have gotten there, and – out-of-it-wise – we’re way more advanced than the Aussies. Our best poets sing of it:

Let us go then, you and I,
Where America is spread out against the sky
Like a nation etherized upon a table…

In one particular way, Australia looked for awhile as though it might overtake us – i.e., in government-sponsored anti-psychotic dosing of children without psychotic symptoms.

To be sure, we’ve got Joseph Biederman (type his name into this blog’s search engine and enjoy).

But Australia’s got Patrick McGorry who, until he (under pressure from scientists around the world) abandoned the idea, thought it might be clever to experiment with giving fifteen-year-olds he determined to be “pre-psychotic” powerful antipsychotic drugs. Some people thought it wasn’t too cool to give “children who had not yet been diagnosed with a psychotic illness…. drugs with potentially dangerous side effects.” So last summer McGorry dropped the idea.

And now – under equally strong pressure from an outraged scientific community, McGorry has gone one step further.

Concerns about the overmedication of young people and rigid models of diagnosis have led the architect of early intervention in Australian psychiatry, Patrick McGorry, to abandon the idea pre-psychosis should be listed as a new psychiatric disorder.

The former Australian of the Year had previously accepted the inclusion of pre-psychosis – a concept he and colleagues developed – in the international diagnostic manual of mental disorders, or DSM, which is being updated this year.

Drug companies must be mildly dismayed. (Only mildly, because they’ll find a way around this.) Popular American news shows are pointing out that for most people anti-depressants are placebos with serious side effects. Critics are attacking the idea of a grief pill. And now the packed-with-potential idea of pre-psychosis (who ain’t pre-? and when will they figure out that an even niftier idea is clinically pre-neurotic?) is being savaged simply because some people think giving symptom-free people immensely powerful drugs is unethical!

Zoom in on the bigger picture here, if you will. Through incessant advertising, and through incentivized research professors at our universities, the drug industry is slowly rebuilding our basic human self-appraisals. We simply cannot get through life without pills.

February 19th, 2012
Will it make any difference that tonight 60 Minutes will air…

… an “explosive” segment on anti-depressants as no better than placebos for the vast majority of people taking them? Will it be, as promised, explosive? Harvard’s Irving Kirsch will talk about his research, featured in The Emperor’s New Clothes: Exploding the Antidepressant Myth – another promised explosion. Marcia Angell’s review of his and other books on the subject in the New York Review of Books was also, I guess, explosive… But so far that essay prompted only a flaccid little response from Peter Kramer in the New York Times.

We’ve heard nothing from the companies that make billions of dollars off the sale of do-nothing, stuffed-with-side-effects drugs except for what they told Stahl: They work. Kramer said the same thing: “[I]t is dangerous for the press to hammer away at the theme that antidepressants are placebos. They’re not.”

Dangerous!

But why are Kramer and company doing little other than repeating, while speaking darkly of risk, that antidepressants work?

Et alors. I’m not sure major attention even of the sort 60 Minutes represents will constitute a bombshell. Positions here are and have long been entrenched, and you don’t exactly kiss goodbye a ten billion dollar enterprise without a struggle.

And millions of Americans – despite witnessing an extremely loud and incredibly close prescription pill epidemic – seem wedded to a sense of themselves as chemically dependent. Indeed to a sense of life itself as the sort of thing you need Prozac to pursue.

February 6th, 2012
“[I]n this most scientific of all ages, pseudoscience seems to be flourishing.”

A distinguished Australian scientist says what those of us who have giggled through Don DeLillo’s White Noise know: The smarter we get, the dumber we get. The Age of Information is The Age of the Idjit. “The greater the scientific advance,” one of DeLillo’s characters explains, “the more primitive the fear.”

So universities have to be careful, because millions of highly advanced people believe all sorts of bullshit, especially about medical therapies (“chiropractic, homeopathy, iridology and reflexology”) that don’t belong in university degree programs because no empirical basis exists for them and because they divert resources from legitimate therapies. This blog has chronicled the efforts – often successful in the US – of reputable scientists to keep reputable universities from starting chiropractic programs in particular. A group of concerned international scientists is now “urging the vice chancellors [of Australian universities] to review the teaching of these courses and come up with a statement on the issue when they meet in March.” Quite a number of Australian universities – many of them public-funded – are handing out degrees in pretty whacked-out stuff.

February 5th, 2012
Sloan Ranger

Big intellectual property lawsuit brewing, with the president of the Sloan-Kettering Cancer Center accused of using research generated at his prior lab – the U Penn’s Leonard and Madlyn Abramson Family Cancer Research Institute – to start up a potentially very, very, profitable pharma outfit.

January 24th, 2012
Can the grief already! Or…

… it’s anti-psychotic time!

December 29th, 2011
Marcia Angell’s Great Essay…

… gets some high-profile attention.

David Brooks, New York Times:

Anybody who is on antidepressants, or knows somebody who is, should read Marcia Angell’s series “The Epidemic of Mental Illness: Why?” from The New York Review of Books. Many of us have been taught that depression arises, in part, from chemical imbalances in the brain. Apparently, there is no evidence to support that.

Many of us thought that antidepressants work. Apparently, there is meager evidence to support that, too. They may work slightly better than placebos, Angell argues, but only under certain circumstances. They may also be permanently altering people’s brains and unintentionally fueling the plague of mental illness by causing episodes of mania, for example. I wouldn’t consider Angell the last word on this, but it’s certainly a viewpoint worth learning about.

The latest study suggests antidepressants work no better than placebos.

UD‘s posts about Angell’s essays are here (scroll down).

December 27th, 2011
‘”I was surprised by the results. They weren’t what I’d expected,” said lead researcher Jacques P. Barber, dean of the Institute of Advanced Psychological Studies at Adelphi University in Garden City, New York.’

Surprised that placebos treat depression just as well as expensive, side-effect-ridden anti-depressant pills? Why?

Start here.

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